Below are the top 30 NHL Draft Prospects, according to ISS Hockey's April 2013 Rankings:
| Rank | Name | Position | Team | League |
| 1 | Seth Jones | D | Portland | WHL |
| 2 | Valeri Nichushkin | C | Chelyabinsk | KHL |
| 3 | Nathan MacKinnon | C | Halifax | QMJHL |
| 4 | Jonathan Drouin | LW | Halifax | QMJHL |
| 5 | Sasha Barkov | C | Tappara | FinE |
| 6 | Darnell Nurse | D | Sault Ste. Marie | OHL |
| 7 | Nikita Zadorov | D | London | OHL |
| 8 | Elias Lindholm | C | Brynas | SweE |
| 9 | Sean Monahan | C | Ottawa | OHL |
| 10 | Bo Horvat | C | London | OHL |
| 11 | Rasmus Ristolainen | D | TPS Turku | FinE |
| 12 | Curtis Lazar | C | Edmonton | WHL |
| 13 | Hunter Shinkaruk | C | Medicine Hat | WHL |
| 14 | Ryan Pulock | D | Brandon | WHL |
| 15 | Alexander Wennberg | C | Djurgarden | SweJE |
| 16 | Valentin Zykov | RW | Baie-Comeau | QMJHL |
| 17 | Kerby Rychel | LW | Windsor | OHL |
| 18 | Andre Burakowsky | LW | Malmo | SweAl |
| 19 | Josh Morrissey | D | Prince Albert | WHL |
| 20 | Frederik Gauthier | C | Rimouski | QMJHL |
| 21 | JT Compher | C | USA Under-18 | NTDP |
| 22 | Steve Santini | D | USA Under-18 | NTDP |
| 23 | Robert Hagg | D | Modo | SweJE |
| 24 | Jason Dickonson | LW | Guelph | OHL |
| 25 | Anthony Mantha | LW | Val d'Or | QMJHL |
| 26 | Max Domi | C | London | OHL |
| 27 | Madison Bowey | D | Kelowna | WHL |
| 28 | Ryan Hartman | RW | Plymouth | OHL |
| 29 | Nic Petan | C | Portland | WHL |
| 30 | Chris Bigras | D | Owen Sound | OHL |
